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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '49f09e596bd089250189bdc48b1225b8df3fa6d0f17ebdf09aed720a3d5ab390' 
  AND token = 'z89laE/lW1ZfRQ8T0qSjhDIjg3a2dlyHFK54zdkyBTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}