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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '546231e75b20279f99f9fb22656b35b588be946f2a158eb96b83041c86c5045f' 
  AND token = 'M1h625UJ+JbMl9GOd2XF66fXJkhtQgiSEpdadECV0Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}