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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1c78c8a27c109bc79310303be479d99f5dcec05f20c1378f3cae86752c21c457' 
  AND token = 'HqTF/EYHAa2QXSZO/71XGaS6W3p/CrKZOggF+EhniEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}