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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6183a8766177a65f79ec04e027160ff978c87f0524d92f9ac3e87b10aa4aad52' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}