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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0065c780088cf4feebdf1a49f60d9b8a2df592e317e70fe0a8e4b85a992e1723' 
  AND token = 'XdscXIAqORGKMUDZj439xjJtLdPtySwWWDuN38dOZEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}