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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '83c5ccd3aa704dcb816c4056f00daeaab0f8916ec83e4729d7f8e06d31750302' 
  AND token = 'S4N/QcTG8PsDF/xpur7DcbTPRhRMbUohGFPvsST1nz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}