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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0de5285379d5f243d7f8bacd93d35201f3241ca55fb98b413e2dc68a007e32a4' 
  AND token = 'EQHCAgHnTpmDm49Y1hK+xorFdkTJbm8oRxikIcazj30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}