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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f4ac0c3288ae372acf4a472c86f40cb091ad867d206a25d215f5e3ca900d148a' 
  AND token = 'DKfcx/m1M3h4ISNzWdq5PecPpWcVAFINaILvAlyRngA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}