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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0507a641c277a3d0df3e415aa3d009c672068c30b6d059794e109b6684a99cda' 
  AND token = 'efeD+cNxcBy+Zo4ZfKYUgUJaziRop/dSkrNBzjOhf7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}