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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '77819f9188ed409792916d1946c6e24c83fd75486f8f097a9299b5a65de66b35' 
  AND token = '42rtfWkzBpaZZxfF++AosMTjny18qWy64PmXaNqJlbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}