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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fba77210f51f59c251d20397a03e717da1dc8ecc567fe3cde7cb72f72a7b3291' 
  AND token = 'NgBdZJcQBl2e5JGaiWQXWmEUC9QCWDZLSTQ6p0XSsUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}