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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c67b6e6847f6eedf1db5b443872b7339a04c80806365d0672e6c19fa37db8afb' 
  AND token = 'Gm17gSJYGO+Tog3PVLXEIGc6xG8Gbo0Gx48WCFBVQFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}