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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43a225949a116e5eb442cf96922b29969376478da101fcd63dc4cd7ef54e5c69' 
  AND token = '32lM9sfOYtIN7CswL+Abvm14JwTscwUc/SbDgGv80sE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}