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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd6776d5bbce2506d8024641eae04d0b86f1f16b5be51ed8c28896d0c52069d8b' 
  AND token = 'Hlz7UQeUynWnAWscWFFLhfGmS2gSOKu/VdSsrpgh3oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}