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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4e3166a14f0d0af8a7fc634f22f0fb443942f0ac4597e5d479caab8a87eabf28' 
  AND token = 'tMDimmgG0xVHzsfAAVsM3sKKHm8fKdXl2XmV+DtC+KQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}