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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6f50a36d147dfed338b2985f659109c3b293eaa6be596c1f30a0fb109e37033c' 
  AND token = 'ZCY9R4aqcColQ9gjNPGYKeCTOYkZnhn1g+t3FuSCrNk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}