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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '581ffb64a843b7eefc1056447e770f64504561f43a4e6435a2e292460dab8187' 
  AND token = 'KTYMueKopk7SkKbDDNX0BBQXFQFinmxEWfEhXLBiPhQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}