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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cbd2ecdba535eb172554c6212aea1a7ce8688712e64c2a68028a819c09a8c846' 
  AND token = 'Vu7zT36I/dHFSI1gcrDa/zOxjy9uW33CMurAxQvhu5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}