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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '00b259458b1aa2ef4cd40089506598b97bcb40eb36e9c00b4931baa2d81e1e38' 
  AND token = 'Wu1/3OxisnGpWEnMiU/7vZZcsQ3vvuHnbqBl9lj53LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}