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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fd1994f2025b4e5d3de700ee940edce925b0cb9e24c761e604441a51dfac8155' 
  AND token = '+cGbYNOzzGZ9Oe+dBSlzSW3i/UaKLiohJzGjS/6y+NE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}