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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2250c2553ca3c753f8ee06a9d8c0d3ddc3fa3250a64b9d4bc131b72eea3a0943' 
  AND token = 'iOpvjb4Knt2W5MAglZxOiMSxp21erkrj3mcHjvM4aXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}