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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0480d62580ecf9efcdc60cf517a81eed0ce2080de0e25fa79155210b1f6379a0' 
  AND token = 'YXRBrMFCrfyuUGa0BYT6uC5h77OhXVGYTRWnDkaGI+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}