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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '10454a49ceb79a1cda049d7621a42d7b8b34f6b2bb026643c8960b8c37430026' 
  AND token = 'HOseJjzbN1fguQpvP3z1jV2kgDsc78giA1dab3EyxdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}