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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1c4b568d46d9cc2487bce40e65dda5debbd6674619b9a23b1e8c4413e59c42a2' 
  AND token = '6u6GS87fZn7+BG+ODYXa6TWFIfTCdPTOHa2zjXmBLBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}