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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e9b2196b41fec05ef8b06e91d9638b0421265f393076de0217f584398b9f9b4d' 
  AND token = 'baGnw1sTExS9VtkvaPEDk9c06SRLrQ2XvdcdLQL4DVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}