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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '053d043cfe5b307cb35ee8f93bc362299ced3eb1afe879b2ecc55992e9bcaf59' 
  AND token = 'KixPmH5wT6GxGfqLH6lpOXnybDT4kLextXVoLKM92I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}