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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9e6d8c871223f5aefe4c9336fea5df89f6f78b155868bc9e3b5901323cf3b4ef' 
  AND token = 'LsoEE2dMTgjDLE4kWSk61T7PkElx9j5DxbGz3DLSwkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}