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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd200996ce471b3330f6334dd6280a5a31c90435513609c1aa3623701ae96d794' 
  AND token = 'GKI/C4ae/1uPZBKMT+pBAWQWNDz1MfuBEdIBfJdAlKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}