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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ce572aa56e311354ae155bfbd75b4bcf3621f17a7e7332ba47e3291befd3c318' 
  AND token = 'tjWqV3Nbx58TJlRWA86oX6ptY/xOQcR9TKbZCoB0jQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}