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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2818c7a357486fef9ea01f868c9a93efe9b3010e969dcead9a4d3d0aee2587c9' 
  AND token = 'w/0Mr5kHH20fRK2oEWHA6ynE+GyVuJwQt6MGrL6WgkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}