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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cd546d53f4b001fd5693384b830552391f561baec49f287664e98ed5688a0bc8' 
  AND token = 'IjpxE9BHoB8jr0M0m76hWc+hKEx1FEjSnL2A6RrlxnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}