SELECT 
  cscart_aprilproduct_prices.product_id, 
  MIN(
    IF(
      cscart_aprilproduct_prices.percentage_discount = 0, 
      cscart_aprilproduct_prices.price, 
      cscart_aprilproduct_prices.price - (
        cscart_aprilproduct_prices.price * cscart_aprilproduct_prices.percentage_discount
      )/ 100
    )
  ) AS price 
FROM 
  cscart_aprilproduct_prices 
WHERE 
  cscart_aprilproduct_prices.product_id IN (
    165, 166, 86, 106, 105, 247, 101, 33, 32, 
    163, 244, 212, 155, 102, 55, 176, 69, 
    138, 110, 36, 206, 28, 184, 183, 133, 
    132, 125, 120, 223, 225, 224, 146, 147, 
    93, 117, 219, 222, 220, 221, 87, 113, 
    139, 118, 83, 157, 123, 174, 171
  ) 
  AND cscart_aprilproduct_prices.lower_limit = 1 
  AND cscart_aprilproduct_prices.usergroup_id IN (0, 1) 
GROUP BY 
  cscart_aprilproduct_prices.product_id

Query time 0.00117

JSON explain

{
  "query_block": {
    "select_id": 1,
    "cost_info": {
      "query_cost": "149.98"
    },
    "grouping_operation": {
      "using_temporary_table": true,
      "using_filesort": true,
      "cost_info": {
        "sort_cost": "96.00"
      },
      "table": {
        "table_name": "cscart_aprilproduct_prices",
        "access_type": "ALL",
        "possible_keys": [
          "usergroup",
          "product_id",
          "lower_limit",
          "usergroup_id"
        ],
        "rows_examined_per_scan": 254,
        "rows_produced_per_join": 95,
        "filtered": "37.80",
        "cost_info": {
          "read_cost": "34.78",
          "eval_cost": "19.20",
          "prefix_cost": "53.98",
          "data_read_per_join": "2K"
        },
        "used_columns": [
          "product_id",
          "price",
          "percentage_discount",
          "lower_limit",
          "usergroup_id"
        ],
        "attached_condition": "((`vishalecarter_april_setup`.`cscart_aprilproduct_prices`.`lower_limit` = 1) and (`vishalecarter_april_setup`.`cscart_aprilproduct_prices`.`product_id` in (165,166,86,106,105,247,101,33,32,163,244,212,155,102,55,176,69,138,110,36,206,28,184,183,133,132,125,120,223,225,224,146,147,93,117,219,222,220,221,87,113,139,118,83,157,123,174,171)) and (`vishalecarter_april_setup`.`cscart_aprilproduct_prices`.`usergroup_id` in (0,1)))"
      }
    }
  }
}