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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2178ac7f2a7e94cd6ef3a647c38e1e9711bf8047b896fcc757ab7f186f261387' 
  AND token = 'cw7HRgaiI7yNyXiWwlpBBvf+wMc1LH1Qo0BhORii54E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}