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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4092ad6d8ce149be462419cb315d66668e18e74f5fd1ed7ba76f5cd4e7bbf668' 
  AND token = 'afiYF2GCiAVVulvvw8PG3bsAdhkioucLQY+6va8BXcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}