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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f664ca209fee77cd2c1b1a5f2e67fc50dc08588532f938c38f17e98a7ea9af53' 
  AND token = 'Q/l2L09fp6acXNDwb5UCrBwBldKpeZLTS4F1N4ZgJP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}