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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46459a6cc28cbb9aaafd12b9343e38e48b656131cbd83554bce2adff243d4e8e' 
  AND token = 't6vFnn5nzTsJcBtRopMPzV8uO+uSNA8SmWrDiPky0ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}