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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b87282537b4eb3d0286c30e954bd977c649d89d22953dae7ffc97772e1797a3d' 
  AND token = 'gmsyVV12QdxL58Yd+I+e0jN6dHOHKgPQyw7n2MzukSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}