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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4412f499810e6565ec2644daacbaa9365051f2b3587667d9a1fa086b10ac8809' 
  AND token = 'sEeOC7Yv0vFrSFT2rjOqBWI7lpdnb2RoMI7Gu7zr2Gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}