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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1001c391164a9b0fadc196ad58ba89228364de164c7d9ac7f4564987eb35d477' 
  AND token = 'TofU+sr9UQx7JbwS6mb/mG8AmlAaF1FzDh2M2nc8STQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}