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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '685658a6a62defcd85098a14fab129174cc8ad7cda04d0a3dba89e969c5fb373' 
  AND token = 'Bd5UrU7SYHoiiLdhI0Y1DTZhLbCOyei7g8FvxHATmrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}