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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ab2fe466edc1cd381104352add2c14e083e8123077cb20887fa268609e4d11c9' 
  AND token = 'JvfHZMH24tkRt6Ivhoq7IlwUNlSfKJDcVa3WVqL3okE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}