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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fbaf49eaf82cc4147a171618fefb96daf558345bb3196eea75e9d0b2dd972754' 
  AND token = 'GaOf8Vrhx7oPGEpPmD0gWSWiKBpc0PxXDYZa8GO/5Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}