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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e3629fbe25b332bfc4a765b27780886159673f4d80244e95af66570ca1a02cd1' 
  AND token = '+Rbeh1amMz2/Q6ErDUAglSV3QJ2PeO0GKiaeXbN6t2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}