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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '08f0fb78f5f4b1b5fdb8782be67cf90242d7127760d53a90b4b4a439eb936845' 
  AND token = 'ZZODHXOTKepy1fQFARLTNEP23mx9irCC79YJckLMkYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}