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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '95ea2eabb36b81e6bb7a99c2536890cdc936188f663d78817b7a1774e4aa9296' 
  AND token = 'Fdmiu2KBSG9tx49TfGGPFuUkihTPKA9L/KIBLE/UGxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}