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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '24c04350df041db76c034be3b8075806ec8624d662849435beed5a6a28a7e88c' 
  AND token = 'GMzfRLo0EEJaeKT0DLZCjIDdYKkm0acGRqrfPDFllbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}