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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2418e8f225418cd8a2e0107f6717635eb8649ed5bb1f71628298039df0c2bb5a' 
  AND token = 'ywORhO4ZMeP7OMQh6OLevKbDyr3PFDSBc3BKPxwgQKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}