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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aef340e9ed25da4b13f47751e5a23df452881022c291a5b8e90b504e01433825' 
  AND token = 'GLtleMT9RwYj4oj1BjtLPogpA74GQqgk1xDVW57/hBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}