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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46b6c87191f8bb81df9617be5cc2b65f5ac1536dd9acf573c23d83d689f88feb' 
  AND token = 'Icqq2C+Feg7MLvdgdt3mCTnW0tVhyaQrW6dD8yGKfCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}