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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0fa64e9fb67f76e0712ef6c1ca5770a9969456dbac3df0a4b69e14664998d27e' 
  AND token = 'efQZTOTzwUaMJGOcQqrxeLBAPl2JQQRt+67QtkdBbr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}